Signature Skin Booster — Deep Skin Renewal & Collagen Stimulation (Onnyx)

The Signature Skin Booster is a deep skin-renewal approach that combines techniques and regenerative agents to stimulate your skin to build collagen naturally, helping it look stronger, more supple, smoother, and healthier from within. Several programs are available — Onnyx Signature, First Class, Juvelook, and Belotero Revive — and results appear gradually and vary by individual. A doctor designs and performs every step of the treatment.

What is the Signature Skin Booster?

The Signature Skin Booster is a deep skin-renewal protocol designed by the clinic, pairing agents and techniques that focus on collagen stimulation (collagen stimulator / biostimulator) with hydration and skin nourishment. The goal is not just temporary volume — it is to recondition the skin so it becomes stronger and recovers better over the long term. Your doctor selects the program and the number of sessions to suit each individual’s skin condition.

What does the Signature Skin Booster help with?

This program focuses on the structure and quality of the skin rather than fixing one isolated concern:

• Stimulates collagen production — helps the skin build new collagen and elastin naturally
• Deep skin renewal — reconditions tired, dull skin so it looks healthier
• Adds strength and resilience — skin looks firmer, more elastic, and smoother
• Boosts hydration and radiance — skin looks plump and the complexion looks brighter
• Cares for early sagging — suited to skin beginning to lose firmness with age

What’s included in the Signature Skin Booster?

Each program has its own strengths and ingredients, so you can choose based on your skin condition and goals. Your doctor will help recommend the program that suits you on the consultation day:

What is Juvelook?

Juvelook is a new-generation hybrid collagen stimulator that combines microparticles of PDLLA (Poly-D,L-Lactic Acid) with hyaluronic acid (HA) in a single formulation. The HA hydrates the skin for immediate plumpness, while the PDLLA gradually stimulates skin cells (fibroblasts) to build new collagen and elastin over the following weeks to months. It therefore differs from a conventional filler that focuses on temporary volume, because Juvelook aims to restore the quality and structure of the skin from within.

How does Juvelook work?

After the injection, HA makes the skin look hydrated and more radiant in the early phase, while the PDLLA acts as a scaffold for the skin to build new collagen gradually. Over time, the PDLLA breaks down naturally and is cleared by the body, while the newly formed collagen continues to support the skin’s structure — making the skin look stronger and more elastic in a natural way. The degree of response and the results vary by individual.

What is Belotero Revive

Belotero Revive is a premium skin booster in the Signature Skin Booster group that combines hyaluronic acid with glycerol to deliver deep hydration to the skin. It helps the skin look dewy and smooth and cares for overall skin quality. It suits dry, dehydrated skin, skin that looks tired, or skin beginning to show fine lines from dehydration. Results vary by individual, and your doctor will always assess your suitability before treatment.

Where can collagen stimulation be injected?

Collagen-stimulating agents such as Juvelook can treat many areas, on both the face and the body. Your doctor selects the placement and the amount to suit each individual’s skin condition and goals:

• Forehead and temples — helps the skin look smoother and more radiant
• Cheeks and nasolabial folds — adds firmness for a naturally fuller look
• Under-eye and the eye area — cares for thin, tired-looking under-eye skin (assessed individually)
• Neck — renews neck skin that is beginning to lose firmness
• Body skin, such as the upper arms and abdomen — cares for skin lacking smoothness and elasticity

Injections with the Hycoox device at Onnyx Clinic

At Onnyx Clinic, you can choose to have the Signature Skin Booster injected with the Hycoox device, an injector with a fine tip that distributes the product evenly and precisely into the skin, controls the amount delivered at each point, and hurts less than a manual injection. It suits people who are worried about pain or who want the regenerative agents spread thoroughly. Your doctor assesses and selects the injection method that suits each person’s skin.

How do the different collagen-stimulating programs differ?

Within the collagen-stimulating (biostimulator) family there are several types that work differently depending on the base agent. The table below makes the overview easier to understand; your doctor will recommend the type that suits you, and the timeframes given are approximate and vary by individual:

Note: The information above is a general overview for initial understanding. The programs Onnyx Clinic designs select the agents and techniques to suit each individual’s skin condition, chosen by a doctor.

Can collagen stimulation be combined with other treatments?

Generally, it can be planned together with other treatments — such as botulinum toxin, filler, laser, or mesotherapy — on your doctor’s advice, because each treatment works in a different way and they complement one another. For example, collagen stimulation can refine skin quality alongside filler that fills deeper grooves. Your doctor will assess the order and spacing of each treatment to keep it appropriate and safe for each individual.

Who is the Signature Skin Booster for, and who should avoid it?

Suitable for those who want deep skin renewal and natural collagen stimulation, skin that is beginning to sag or lose firmness, skin that looks tired, dull, or dehydrated, or anyone seeking natural skin care that focuses on long-term skin quality.

Tell your doctor or avoid if you are pregnant or breastfeeding, have an infection or inflammation at the treatment area, have a history of allergy to the product’s components, or have certain underlying conditions. Your doctor will take a history and assess suitability before every treatment.

The treatment steps at Onnyx Clinic

1. Consultation and skin assessment — your doctor discusses your goals and examines your skin condition.
2. Designing the program — selecting the program and the appropriate number of sessions for each individual; multiple techniques may be combined.
3. Treatment by a doctor — careful and precise care.
4. After-care and follow-up — guidance on care and scheduled follow-up according to the plan.

How many sessions until you see results from the Signature Skin Booster?

Because the program focuses on stimulating collagen — which the body needs time to build anew — results appear gradually and become clearer as you continue according to the plan your doctor sets. The timeframes below are approximate and vary by individual:

How long do the results last?

Because the program’s effect comes from collagen the skin builds itself, results develop gradually and last for a period. Generally, collagen-stimulating agents such as Juvelook deliver results lasting several months up to around a year or so, depending on the type of agent, skin condition, lifestyle, and individual care. Repeating on the cycle your doctor recommends helps maintain results over time. Results vary by individual.

How is the Signature Skin Booster different from filler and mesotherapy?

All three work differently and serve different needs; many people use them together on their doctor’s advice:

Is the Signature Skin Booster safe, and what side effects can occur?

The program is safe when performed by a doctor with standard-grade products in a licensed medical facility. Side effects are usually mild and temporary — such as redness, swelling, or slight bruising at the treatment area — which usually improve on their own within a few days. Having the procedure done by a non-doctor or with substandard products is the most significant risk, so you should choose a licensed medical facility and have the treatment performed by a doctor.

Preparing before treatment

• Tell your doctor about any underlying conditions, medications, and allergy history.
• Pause medications/supplements that may cause easy bleeding as advised by your doctor.
• Avoid alcohol before treatment and arrive with clean skin.
• Avoid undergoing treatment while the skin has inflammation or infection.

After-care

• Avoid pressing, massaging, or scrubbing the treated area in the early period.
• Skip makeup for about 24 hours.
• Avoid strong sunlight and apply sunscreen regularly.
• Avoid sauna, high heat, and strenuous exercise in the early period.
• Mild redness or swelling may occur and will gradually improve; if you have any questions, you can consult your doctor at any time.

Mild swelling or redness usually improves within a few days, and most people need little downtime and can return to daily life. During the procedure, a doctor typically uses a local anesthetic to help reduce discomfort. The response and recovery time vary by individual.

Why choose the Signature Skin Booster at Onnyx Clinic?

Designed and performed by a doctor, using standard-grade products, with the option to be injected with the Hycoox device with a fine tip that distributes the product well and hurts less, with programs tailored to each individual, transparent pricing, and close before- and after-care — for results that look natural and are safe by medical standards. Results vary by individual.

References

• Thai Food and Drug Administration (Thai FDA, อย.) — fda.moph.go.th
• American Academy of Dermatology — aad.org
• U.S. Food & Drug Administration — fda.gov